SR-9011 (5mg/capsule), 60 Capsules

Description

SR-9011 is a potent, synthetic Rev-ErbA agonist engineered specifically for advanced biochemical and pharmacological research. Initially developed to study the molecular mechanisms governing circadian rhythms and metabolic homeostasis, SR-9011 binds to Rev-Erb$\alpha$ and Rev-Erb$\beta$ nuclear receptors with high affinity. By modulating these core transcriptional repressors, SR-9011 serves as a pivotal tool for scientists exploring lipid metabolism, energy expenditure, mitochondrial biogenesis, and muscle tissue adaptation in vitro and in preclinical animal models.

Although often grouped alongside Selective Androgen Receptor Modulators (SARMs) due to its popular investigation in endurance and body composition models, SR-9011 is non-hormonal. It operates entirely independently of androgenic, estrogenic, or anabolic pathways. Instead, its primary mechanism hinges on altering gene expression within hepatic, adipose, and skeletal muscle cells, making it an invaluable reference agent for metabolic disease models and exercise mimetic research.

Composition, Encapsulation & Quality Standards

Each bottle contains 60 oral capsules, with each capsule delivering exactly 5mg of high-purity SR-9011 compound ($300\text{mg}$ total yield per unit). The active compound is blended with inert microcrystalline cellulose inside pharmaceutical-grade gelatin capsules to ensure uniform distribution and precise administration during laboratory trials.

• Chemical Name: ethyl 3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]pyrrolidine-1-carboxylate

• CAS Registry Number: 1379686-30-2

• Molecular Formula: $\text{C}_{19}\text{H}_{21}\text{ClN}_2\text{O}_4\text{S}$

• Molar Mass: 408.90 g/mol

• Purity Rating: $\ge 98\%$ purity (verified via High-Performance Liquid Chromatography)

• Formulation Standards: Synthesized and processed using modern automated micro-encapsulation methods to prevent oxidation and ensure batch-to-batch structural integrity.

Primary Research & Application Areas

Laboratory interest in SR-9011 spans several domain disciplines across physiology and cellular biochemistry:

1. Circadian Rhythm Modulation: Researchers utilize SR-9011 to examine how Rev-Erb activation alters central and peripheral biological clocks, investigating gene expression shifts across light-dark cycles.

2. Mitochondrial Biogenesis: In skeletal muscle assays, SR-9011 administration correlates with increased mitochondrial count and respiratory capacity, aiding studies on oxygen consumption and cellular stamina.

3. Lipid & Glucose Homeostasis: Investigators analyze SR-9011 to monitor hepatic lipogenesis suppression, fat storage attenuation, and enhanced glucose uptake in metabolic disease models.

4. Inflammatory & Cardiovascular Signaling: Preclinical trials explore Rev-Erb activation in vascular endothelial cells to track cytokine release, arterial wall stress, and systemic inflammatory responses.

Analytical Integrity & Customer Satisfaction

Maintaining rigorous standards is critical for modern scientific investigation. Every lot of SR-9011 undergoes comprehensive third-party testing, including HPLC, Mass Spectrometry (MS), and microbiological screening. A batch-specific Certificate of Analysis (CoA) accompanies every order, allowing research facilities to verify purity and concentration before beginning protocol trials. Dedicated customer care, rapid global fulfillment, and strict privacy protection ensure complete satisfaction for institutional and independent research partners worldwide.

Disclaimer: SR-9011 is strictly intended for scientific laboratory research, analytical testing, and educational investigations. It is not approved for human or veterinary consumption, medical treatment, cosmetic application, or agricultural deployment.

Product Specifications Table

Parameter	Specification Details
Brand	Specialized Research Fine Chemicals
Composition / Ingredients	SR-9011 ($\ge 98\%$ purity), Microcrystalline Cellulose, Gelatin Capsule
Concentration / Volume	5mg per capsule / 60 Capsules per bottle ($300\text{mg}$ total)
Duration of Effects	Biological half-life in vivo ranges from 2 to 4 hours; requires scheduled interval dosing in long-term assays
Indications / Usage Areas	Rev-ErbA agonist research, circadian rhythm assays, mitochondrial biogenesis studies, metabolic research
Administration / Method	Laboratory reagent deployment (In vitro / Oral administration in animal models)
Shelf Life	24 Months from production date (Unopened)
Storage Conditions	Store in a cool, dry place ($15^\circ\text{C}$ to $25^\circ\text{C}$); shield from direct heat, light, and humidity
Package Contents	Sealed amber pill bottle with tamper-evident induction seal and desiccant pack
Country of Origin	Manufactured in ISO-certified cGMP facilities (USA / EU sourcing)
Licensing / Certification	ISO 9001:2015 Certified Manufacturing Standard; HPLC/MS Quality Verified
Safety Notes / Side Effects	Laboratory personnel must wear protective gloves, eye protection, and lab coats. Dust contact may cause mild eye or skin irritation.